Compile Data Set for Download or QSAR
maximum 50k data
Found 579 of kd data for polymerid = 50000055,50000237,50000267,50000270,50000272
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50075366((2E,4E)-3-Methyl-5-{2-[(E)-2-(2,6,6-trimethyl-cycl...)
Affinity DataKd: >0.00100nMAssay Description:Inhibition of [3H]-RA binding to retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Affinity DataKd: >0.00100nMAssay Description:Inhibition of [3H]-9-cis RA binding to Retinoid X receptor RXR gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50075367((2E,4E)-3-Methyl-5-{2-[(E)-2-(2,6,6-trimethyl-cycl...)
Affinity DataKd: >0.00100nMAssay Description:Inhibition of [3H]-RA binding to retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50075366((2E,4E)-3-Methyl-5-{2-[(E)-2-(2,6,6-trimethyl-cycl...)
Affinity DataKd: >0.00100nMAssay Description:Inhibition of [3H]-RA binding to retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50075367((2E,4E)-3-Methyl-5-{2-[(E)-2-(2,6,6-trimethyl-cycl...)
Affinity DataKd: >0.00100nMAssay Description:Inhibition of [3H]-RA binding to retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50075366((2E,4E)-3-Methyl-5-{2-[(E)-2-(2,6,6-trimethyl-cycl...)
Affinity DataKd: >0.00100nMAssay Description:Inhibition of [3H]-RA binding to retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50075367((2E,4E)-3-Methyl-5-{2-[(E)-2-(2,6,6-trimethyl-cycl...)
Affinity DataKd: >0.00100nMAssay Description:Inhibition of [3H]-RA binding to retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Affinity DataKd: >0.00100nMAssay Description:Inhibition of [3H]-9-cis RA binding to Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Affinity DataKd:  0.200nMAssay Description:Dissociation constant for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Affinity DataKd:  0.300nMAssay Description:Apparent binding constant against Retinoic acid receptor gamma in HeLa cell GAl-4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50101445((2E,4E)-3-Methyl-5-[(1S,2S)-2-methyl-2-(5,5,8,8-te...)
Affinity DataKd:  0.400nMAssay Description:Dissociation constant for Retinoid X receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Affinity DataKd:  0.400nMAssay Description:Apparent binding constant for Retinoic acid receptor beta in HeLa cellGAL-4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50101445((2E,4E)-3-Methyl-5-[(1S,2S)-2-methyl-2-(5,5,8,8-te...)
Affinity DataKd:  0.400nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to baculovirus expressed retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)
Affinity DataKd:  0.800nMAssay Description:Dissociation constant for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50051553(6-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataKd:  1.10nMAssay Description:Apparent binding constant for Retinoic acid receptor beta in HeLa cellGAL-4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM31886(CD564 | CHEMBL309282)
Affinity DataKd:  1.20nMAssay Description:Apparent binding constant for Retinoic acid receptor beta in HeLa cellGAL-4 transactivation assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50051553(6-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataKd:  1.30nMAssay Description:Apparent binding constant against Retinoic acid receptor gamma in HeLa cell GAl-4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)
Affinity DataKd:  1.5nMAssay Description:Dissociation constant for Retinoid X receptor alphaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50101444((E)-3-Methyl-5-[2-methyl-2-(5,5,8,8-tetramethyl-5,...)
Affinity DataKd:  1.5nMAssay Description:Compound was tested for binding affinity against retinoic acid receptor using 5 nM of [3H]-RA as a radioligand in baculovirus expressed receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50101444((E)-3-Methyl-5-[2-methyl-2-(5,5,8,8-tetramethyl-5,...)
Affinity DataKd:  1.5nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to baculovirus expressed retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50471288(CHEMBL312198)
Affinity DataKd:  1.5nMAssay Description:Inhibition of [3H]ATRA binding to baculovirus expressed RAR alpha receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50051554(6-[2,2-Difluoro-1-(5,5,8,8-tetramethyl-5,6,7,8-tet...)
Affinity DataKd:  1.70nMAssay Description:Apparent binding constant for Retinoic acid receptor beta in HeLa cellGAL-4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50120066(2-Fluoro-4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydr...)
Affinity DataKd:  2nMAssay Description:Binding affinity fo retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50029774(4-(5,5-Dimethyl-8-p-tolyl-5,6-dihydro-naphthalen-2...)
Affinity DataKd:  2nMAssay Description:Binding constant for baculovirus-expressed Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50029774(4-(5,5-Dimethyl-8-p-tolyl-5,6-dihydro-naphthalen-2...)
Affinity DataKd:  2nMAssay Description:Binding constant for baculovirus-expressed Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50122351((2E,4E)-3-Methyl-6-[1-(5,5,8,8-tetramethyl-5,6,7,8...)
Affinity DataKd:  2nMAssay Description:Inhibition of [3H]-9-cis-RA binding to human Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Affinity DataKd:  2.30nMAssay Description:Apparent binding constant against Retinoic acid receptor alpha in HeLa cell GAl-4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50101444((E)-3-Methyl-5-[2-methyl-2-(5,5,8,8-tetramethyl-5,...)
Affinity DataKd:  2.5nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to baculovirus expressed retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50101444((E)-3-Methyl-5-[2-methyl-2-(5,5,8,8-tetramethyl-5,...)
Affinity DataKd:  2.5nMAssay Description:Compound was tested for binding affinity against retinoid X receptor using 5 nM of [3H]-9-cis-RA as a radioligand in baculovirus expressed receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50471290(CHEMBL81978)
Affinity DataKd:  2.80nMAssay Description:Inhibition of [3H]ATRA binding to baculovirus expressed RAR alpha receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50031458((2Z,5E)-7-Methyl-3-[(E)-2-(2,6,6-trimethyl-cyclohe...)
Affinity DataKd:  3nMAssay Description:Binding affinity for human Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50120063(2,6-Difluoro-4-[(3-hydroxy-5,5,8,8-tetramethyl-5,6...)
Affinity DataKd:  3nMAssay Description:Effective concentration for retinoic acid receptor RAR alpha transcriptional activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM31886(CD564 | CHEMBL309282)
Affinity DataKd:  3nMAssay Description:Apparent binding constant against Retinoic acid receptor gamma in HeLa cell GAl-4 transactivation assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Affinity DataKd:  3nMAssay Description:In vitro binding affinity for Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50032671(6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPH...)
Affinity DataKd:  3nMAssay Description:Ability to bind directly to Retinoic acid receptor RXR-alpha was evaluated in a competitive binding assay.More data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)
Affinity DataKd:  3nMAssay Description:Inhibition of binding to human Retinoic acid receptor RXR DEF domainMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50029774(4-(5,5-Dimethyl-8-p-tolyl-5,6-dihydro-naphthalen-2...)
Affinity DataKd:  3nMAssay Description:Binding constant for baculovirus-expressed Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50120065(4-[(4-Chloro-3-hydroxy-5,5,8,8-tetramethyl-5,6,7,8...)
Affinity DataKd:  3nMAssay Description:Binding affinity fo retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50122348((2E,4E)-6-[1-(3,5-Di-tert-butyl-phenyl)-cyclopropy...)
Affinity DataKd:  3nMAssay Description:Inhibition of [3H]-9-cis-RA binding to human Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50051552(6-[HYDROXYIMINO-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRA...)
Affinity DataKd:  3.30nMAssay Description:Apparent binding constant against Retinoic acid receptor gamma in HeLa cell GAl-4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50101445((2E,4E)-3-Methyl-5-[(1S,2S)-2-methyl-2-(5,5,8,8-te...)
Affinity DataKd:  3.60nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to baculovirus expressed retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50601992(CHEMBL5200645)
Affinity DataKd:  3.60nMAssay Description:Binding affinity to human RXRalpha LBD (T225 to T462 residues) by fluorescence quenching assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50075880(4-(5,5-Dimethyl-8-p-tolyl-5,6-dihydro-anthracen-2-...)
Affinity DataKd:  4nMAssay Description:Binding affinity of [3H]- RA to baculovirus expressed human Retinoic acid receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50097820(4-[(E)-4-(3,3-Dimethyl-6-p-tolyl-cyclohexa-1,5-die...)
Affinity DataKd:  4nMAssay Description:Binding affinity towards retinoic acid receptor gamma was determined using [3H]-ATRA (5 nM) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50097821(4-{(E)-4-[2-(4-Ethyl-phenyl)-6,6-dimethyl-cyclohex...)
Affinity DataKd:  4nMAssay Description:Ability to inhibit TTNPB-induced transactivation at retinoic acid receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50052412(4-[(4-Bromo-3-hydroxy-5,5,8,8-tetramethyl-5,6,7,8-...)
Affinity DataKd:  4nMAssay Description:Binding affinity fo retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50601994(CHEMBL5169878)
Affinity DataKd:  4.10nMAssay Description:Binding affinity to human RXRalpha LBD (T225 to T462 residues) by fluorescence quenching assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50052413(4-[(4-Bromo-3-hydroxy-5,5,8,8-tetramethyl-5,6,7,8-...)
Affinity DataKd:  4.40nMAssay Description:Binding affinity for baculovirus-expressed Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50601993(CHEMBL5190999)
Affinity DataKd:  4.70nMAssay Description:Binding affinity to human RXRalpha LBD (T225 to T462 residues) by fluorescence quenching assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50097822(4-{(E)-4-[2-(4-tert-Butyl-phenyl)-6,6-dimethyl-cyc...)
Affinity DataKd:  5nMAssay Description:Binding affinity towards retinoic acid receptor gamma was determined using [3H]-ATRA (5 nM) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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